Regulation of Apoptosis by Inhibitors of Apoptosis (IAPs)

Jean Berthelet, Laurence Dubrez

Cells

MitophagyChemoprevention StrategyApoptosisImmunologyCell Death +15

HMG-CoA reductase promotes protein prenylation and therefore is indispensible for T-cell survival

Sonja M. Lacher, Julia Bruttger, Bettina Kalt, +4

Cell Death and Disease

Targeting triple-negative breast cancers with the Smac-mimetic birinapant

Najoua Lalaoui, Delphine Mérino, Göknur Giner, +17

Cell Death and Differentiation

Cellular Inhibitor of Apoptosis Protein-1 (cIAP1) Can Regulate E2F1 Transcription Factor-mediated Control of Cyclin Transcription

Jessy Cartier, Jean Berthelet, Arthur Marivin, +10

Journal of Biological Chemistry

The site of breast cancer metastases dictates their clonal composition and reversible transcriptomic profile

Jean Berthelet, Verena C. Wimmer, Holly J. Whitfield, +18

Science Advances

Breast OncologyClonal CompositionCancer BiologyTumor BiologyBreast Cancer Progression +18

Apoptosis inhibitor 5 is an endogenous inhibitor of caspase‐2

Gergely Imre, Jean Berthelet, Jan Heering, +6

EMBO Reports

MedicineApoptosisPharmacologyCell DeathApoptosis Inhibitor 5 +2

Proteogenomics analysis unveils a TFG-RET gene fusion and druggable targets in papillary thyroid carcinomas

Aswini Krishnan, Jean Berthelet, Emilie Renaud, +14

Nature Communications

The Inhibitor of Apoptosis (IAPs) in Adaptive Response to Cellular Stress

Arthur Marivin, Jean Berthelet, Stéphanie Plenchette, +1

Cells

Cellular StressApoptosisImmunologyCell DeathOxidative Stress +16

DNA damage and S phase-dependent E2F1 stabilization requires the cIAP1 E3-ubiquitin ligase and is associated with K63-poly-ubiquitination on lysine 161/164 residues

Valérie Glorian, Jennifer Allègre, Jean Berthelet, +13

Cell Death and Disease

cIAP1 regulates TNF-mediated cdc42 activation and filopodia formation

Arthur Marivin, Jean Berthelet, Jessy Cartier, +8

Oncogene

Protein FunctionSignal TransductionTnf-mediated Cdc42 ActivationSignaling PathwayCellular Biochemistry +4