Regulation of the Concentration or Activity of Pyruvate Kinase in Yeasts and its Relationship to Gluconeogenesis

Abstract

rate constant k-4. Modifiers that increase the rate of the isomerization process E'S-E"S will cause a rate increase at low substrate concentrations and co-operativity with respect to the substrate would be abolished if the value of k+2 is increased suffi- ciently for the inequality k+2 k+3 to hold.