Sensitization of Melanoma Cells for Death Ligand TRAIL Is Based on Cell Cycle Arrest, ROS Production, and Activation of Proapoptotic Bcl-2 Proteins

Tumoricidal activity of tumor necrosis factor–related apoptosis–inducing ligand in vivo

Henning Walczak, Robert E. Miller, K. Ariail et al. · Nature Medicine · 1999 · 2.5K citations

Life Sciences, Oncology, Pharmacology +12

Analysis of apoptosis by propidium iodide staining and flow cytometry

Carlo Riccardi, Ildo Nicoletti · Nature Protocols · 2006 · 1.7K citations

Life Sciences, Cell Biology, Pathology +9

The Bax/Bcl-2 Ratio Determines the Susceptibility of Human Melanoma Cells to CD95/Fas-Mediated Apoptosis

Monika Raisova, Amir M. Hossini, Jürgen Eberle et al. · Journal of Investigative Dermatology · 2001 · 566 citations · Full text

Life Sciences, Cell Biology, Oncology +14

Phase I Dose-Escalation Study of Recombinant Human Apo2L/TRAIL, a Dual Proapoptotic Receptor Agonist, in Patients With Advanced Cancer

Roy S. Herbst, S. Gail Eckhardt, Razelle Kurzrock et al. · Journal of Clinical Oncology · 2010 · 440 citations

Life Sciences, Oncology, Pharmacology +17

Oncogenic NRAS signaling differentially regulates survival and proliferation in melanoma

Lawrence N. Kwong, James C. Costello, Huiyun Liu et al. · Nature Medicine · 2012 · 364 citations · Full text

Medicine, Cancer Biology, Oncology +12