NMR methods for determination of enantiomeric excess.

Abstract

With the dramatic recent growth in importance of asymmetric syntheses, new applications or approaches for analyses of enantiomeric excess (% e.e.) of samples continue to become more essential. Nuclear magnetic resonance (NMR) spectroscopy provides a wide range of powerful methods which are complementary to chromatographic or electrophoretic-based approaches. This present review focuses on representative and selective recent examples (through mid-1999) of English language reports on NMR methods for % e.e. determination.