Brain extracellular space: geometry, matrix and physiological importance.

Ion diffusion modified by tortuosity and volume fraction in the extracellular microenvironment of the rat cerebellum.

Charles Nicholson, J. M. Phillips · The Journal of Physiology · 1981 · 779 citations · Full text

<i>In vivo</i> diffusion analysis with quantum dots and dextrans predicts the width of brain extracellular space

Robert G. Thorne, Charles Nicholson · Proceedings of the National Academy of Sciences · 2006 · 620 citations · Full text

High-flow microinfusion: tissue penetration and pharmacodynamics

Paul F. Morrison, Douglas W. Laske, Hunt Bobo et al. · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · 1994 · 318 citations

Engineering, Reperfusion Injury, Medicine +15

Hindered diffusion of high molecular weight compounds in brain extracellular microenvironment measured with integrative optical imaging

Charles Nicholson · Biophysical Journal · 1993 · 260 citations · Full text

Drug “Diffusion” within the Brain^a

Joseph D. Fenstermacher, Thomas G. Kaye · Annals of the New York Academy of Sciences · 1988 · 136 citations

Neurotransmitter, Social Sciences, Blood Flow +17