MGMT gene silencing and benefit from temozolomide in glioblastoma

Unknown author(s)

University of Regensburg Publication Server (University of Regensburg) · 2005 · 341 citations · 0 references

Concepts

Abstract

Patients with glioblastoma containing a methylated MGMT promoter benefited from temozolomide, whereas those who did not have a methylated MGMT promoter did not have such a benefit.