Targeting mitochondrial reactive oxygen species to modulate hypoxia-induced pulmonary hypertension

Mitochondrial reactive oxygen species trigger hypoxia-induced transcription

Navdeep S. Chandel, Emin Maltepe, Eugene Goldwasser et al. · Proceedings of the National Academy of Sciences · 1998 · 1.9K citations · Full text

Extension of Murine Life Span by Overexpression of Catalase Targeted to Mitochondria

Samuel E. Schriner, Nancy J. Linford, George M. Martin et al. · Science · 2005 · 1.7K citations

Mitochondrial complex III is required for hypoxia-induced ROS production and cellular oxygen sensing

Robert D. Guzy, Beatrice Hoyos, Emmanuel Robin et al. · Cell Metabolism · 2005 · 1.5K citations · Full text

Mitochondrial Function, Biochemistry, Natural Sciences +9

NADPH oxidase 4 (Nox4) is a major source of oxidative stress in the failing heart

Junya Kuroda, Tetsuro Ago, Shouji Matsushima et al. · Proceedings of the National Academy of Sciences · 2010 · 764 citations · Full text

Therapeutic Targeting of Mitochondrial Superoxide in Hypertension

Anna Dikalova, Alfiya Bikineyeva, Klaudia Budzyn et al. · Circulation Research · 2010 · 719 citations · Full text