Peptide Drug Delivery to the Brain

Unknown author(s)

Annals of Internal Medicine · 1992 · 309 citations · 0 references

Concepts

Abstract

Biological diversity of peptides peptides as potential neuropharmaceuticals in disorders of the brain overview of blood-brain barrier transport biology and experimental methodologies transnasal and intraventricular delivery of drugs peptide lipidization and liposomes bulk flow and receptor-mediated transcytosis of peptides through the blood-brain barrier absorptive-mediated transcytosis of peptides through the blood-brain barrier antibody delivery through the blood-brain barrier chimeric peptide pharmaceutical delivery through the blood-brain barrier development of brain-specific transport vectors - a molecular biological perspective.