Concepedia

Molecular modeling based approach, synthesis, and cytotoxic activity of novel benzoin derivatives targeting phosphoinostide 3-kinase (PI3Kα)

Dima A. Sabbah, Musaab Saada, Reema Abu Khalaf, Sanaa K. Bardaweel, Kamal Sweidan, Tariq Al‐Qirim, Amani Al-Zughier, Heba Abdel Halim, Ghassan Abu Sheikha

Bioorganic & Medicinal Chemistry Letters · 2015 · 30 citations · 35 references

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35

Glide:  A New Approach for Rapid, Accurate Docking and Scoring. 1. Method and Assessment of Docking Accuracy

Richard A. Friesner, Jay L. Banks, Robert B. Murphy et al. · Journal of Medicinal Chemistry · 2004 · 9.6K citations

Extra Precision Glide:  Docking and Scoring Incorporating a Model of Hydrophobic Enclosure for Protein−Ligand Complexes

Richard A. Friesner, Robert B. Murphy, Matthew P. Repasky et al. · Journal of Medicinal Chemistry · 2006 · 6.7K citations

High Frequency of Mutations of the <i>PIK3CA</i> Gene in Human Cancers

Yardena Samuels, Zhenghe Wang, Alberto Bardelli et al. · Science · 2004 · 3.4K citations

, , +15

Caspase-3 Is Required for DNA Fragmentation and Morphological Changes Associated with Apoptosis

Reiner U. Jänicke, Michael L. Sprengart, Mas Rina Wati et al. · Journal of Biological Chemistry · 1998 · 1.9K citations · Full text

The PTEN–PI3K pathway: of feedbacks and cross-talks

Arkaitz Carracedo, Pier Paolo Pandolfi · Oncogene · 2008 · 884 citations

, , +5