Ghassan Abu Sheikha

Synthesis, Structure, and Antiproliferative Activity of Selenophenfurin, an Inosine 5‘-Monophosphate Dehydrogenase Inhibitor Analogue of Selenazofurin

Palmarisa Franchetti, Loredana Cappellacci, Ghassan Abu Sheikha et al. · Journal of Medicinal Chemistry · 1997 · 75 citations

Medicinal Chemistry, Bioorganic Chemistry, Chemoprevention Strategy +15

Elaborate ligand-based pharmacophore exploration and QSAR analysis guide the synthesis of novel pyridinium-based potent β-secretase inhibitory leads

Afaf H. Al-Nadaf, Ghassan Abu Sheikha, Mutasem O. Taha · Bioorganic & Medicinal Chemistry · 2010 · 63 citations · Full text

Medicinal Chemistry, Qsar Analysis, Biochemistry +8

Discovery of new cholesteryl ester transfer protein inhibitors via ligand-based pharmacophore modeling and QSAR analysis followed by synthetic exploration

Reema Abu Khalaf, Ghassan Abu Sheikha, Yasser Bustanji et al. · European Journal of Medicinal Chemistry · 2010 · 60 citations · Full text

Medicinal Chemistry, Qsar Analysis, Ligand-based Pharmacophore Modeling +10

Computer-aided design, synthesis, and biological evaluation of new indole-2-carboxamide derivatives as PI3Kα/EGFR inhibitors

Kamal Sweidan, Dima A. Sabbah, Sanaa K. Bardaweel et al. · Bioorganic & Medicinal Chemistry Letters · 2016 · 35 citations · Full text

Combinatorial Chemistry, Medicinal Chemistry, Derivatives +11

Molecular modeling based approach, synthesis, and cytotoxic activity of novel benzoin derivatives targeting phosphoinostide 3-kinase (PI3Kα)

Dima A. Sabbah, Musaab Saada, Reema Abu Khalaf et al. · Bioorganic & Medicinal Chemistry Letters · 2015 · 30 citations · Full text

Molecular Pharmacology, Drug Target, Biochemistry +9