PubMed · 1975 · 66 citations · 0 references
MedicinePharmacokineticsPharmacologyAnesthesiaLocal AnesthesiaPharmacokinetic ModelingAnesthetic Drug PharmacologyAnesthetic PharmacologyGeneral Anesthetic AgentsLocal Anesthetic PharmacokineticsLocal Anesthetic ToxicityLocal AnestheticsLocal Anesthetic TherapySpinal PharmacokineticsTopical Local Anesthetics
Information derived from measurements of blood concentrations of local anaesthetics can be extended by the application of pharmacokinetic anaylsis. A better understanding of quantitative aspects of the disposition and absorption of these drugs should assist the anaesthetist in deciding the optimal agent and dosage for regional block techniques.