Concepedia

Publication | Closed Access

Omeprazole weakly inhibits CYP1A2 activity in man.

16

Citations

0

References

1999

Year

Karl Ludwig Rost, Uwe Fuhr, T. Thomsen, M Zaigler, J Brockmöller, Holger Bohnemeier, Ivar Roots
PubMed

Abstract

Omeprazole exerts a concentration-dependent inhibition of CYP1A2 activity in man. However, even after single oral doses up to 80 mg, this effect is weak and without clinical relevance.