Veterinary MedicineInfectious DiseasesPreventive MedicineImmunizationInfection PreventionVaccinologyClinical Development Of VaccinesClinical Vaccine TrialsVaccinationVaccine EffectivenessVaccine EfficacyVaccine-preventable DiseasesEfficacy Against InfectionField Trial EvaluationMeningococcal ProphylaxisPolysaccharide VaccinesVaccine Clinical Trial Design
A second large-scale field trial of group C meningococcal polysaccharide vaccine in US Army recruits confirmed the efficacy and safety of the vaccine. When the results of all studies over a 2-year period were combined, the reduction in group-specific disease rates was 89.5%.
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HUMAN IMMUNITY TO THE MENINGOCOCCUS
E C Gotschlich, Teh Yung Liu, Malcolm S. Artenstein · The Journal of Experimental Medicine · 1969 · 397 citations · Full text