Tryptase and protease-activated receptor-2 stimulate scratching behavior in a murine model of ovalbumin-induced atopic-like dermatitis

Agonists of proteinase-activated receptor 2 induce inflammation by a neurogenic mechanism

Martin Steinhoff, Nathalie Vergnolle, Steven H. Young et al. · Nature Medicine · 2000 · 931 citations

Life Sciences, Neurobiology, Neuroscience +10

Epicutaneous sensitization with protein antigen induces localized allergic dermatitis and hyperresponsiveness to methacholine after single exposure to aerosolized antigen in mice.

Jonathan M. Spergel, Emiko Mizoguchi, Joanne P. Brewer et al. · Journal of Clinical Investigation · 1998 · 637 citations · Full text

Life Sciences, Dermatology, Immunology +17

Quantitation of histamine, tryptase, and chymase in dispersed human T and TC mast cells.

Louis B. Schwartz, Anne Marie Irani, K. Roller et al. · The Journal of Immunology · 1987 · 501 citations

Life Sciences, Immunology, Pathology +11

Scratching behavior induced by pruritogenic but not algesiogenic agents in mice

Yasushi Kuraishi, Tetsuro Nagasawa, Kazuko Hayashi et al. · European Journal of Pharmacology · 1995 · 404 citations

Life Sciences, Dermatology, Immunology +11

Roles of TH1 and TH2 cytokines in a murine model of allergic dermatitis

Jonathan M. Spergel, Emiko Mizoguchi, Hans C. Oettgen et al. · Journal of Clinical Investigation · 1999 · 386 citations · Full text

Medicine, Dermatology, Immunology +17