ß-endorphin induces general anaesthesia by an interaction with opiate receptors

The Pharmacological Basis of Therapeutics

American Journal of Health-System Pharmacy · 1976 · 8.2K citations

Medicine, Pharmacology, Pharmacotherapy +10

Identification of two related pentapeptides from the brain with potent opiate agonist activity

Joel W. Hughes, Terry Smith, H. W. Kosterlitz et al. · Nature · 1975 · 3.8K citations

Medicine, Medicinal Chemistry, Pharmacology +13

Opiate Receptor: Demonstration in Nervous Tissue

Candace B. Pert, Solomon H. Snyder · Science · 1973 · 2.4K citations

Medicine, Neuroscience, Pharmacology +10

Stereospecific Binding of the Potent Narcotic Analgesic [ ³ H]Etorphine to Rat-Brain Homogenate

Eric J. Simon, Jacob M. Hiller, Irit Edelman · Proceedings of the National Academy of Sciences · 1973 · 1.1K citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Endorphins: Profound Behavioral Effects in Rats Suggest New Etiological Factors in Mental Illness

Floyd E. Bloom, David J. Segal, Nicholas Ling et al. · Science · 1976 · 812 citations

Medicine, Neuroscience, Pharmacology +17