Journal of Forensic Sciences · 1996 · 43 citations · 8 references
PharmacyClinical ToxicologyToxicologyNeurotoxicologySubstance Abuse ToxicologySubstance Use DisordersClinical Manifestations Of IntoxicationDrug Overdose DiagnosisDrug Overdose ManagementOverdose ManagementStimulant ToxicologySubstance IntoxicationAmphetamine ToxicityBlood PressureIllicit Drug DeathsIllicit Drug OverdoseIllicit Drug Poisoning InvestigationMethamphetamine DistributionMethamphetamine ToxicityOverdose Toxicity
A subject who apparently swallowed a baggie containing "crank" (methamphetamine) while being arrested, was admitted to hospital and then experienced a massive overdose of the drug. The subject went through a seizure with associated fixed dilated pupils, and a depressed pulse and blood pressure. His cardiac and respiratory problems could not be stabilized, and he died. Methamphetamine levels in central and peripheral blood, liver, bile, vitreous, gastric and urine were determined. Blood levels of greater than 60 mg/L, were found together with even higher levels in the bile, urine and gastric. These levels are discussed in terms of other fatal, non-fatal and recreational methamphetamine use.
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A fatal methamphetamine poisoning associated with hyperpyrexia
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