Concepedia
Environmental Toxicology and Pharmacology · 2007 · 31 citations · 23 references
Natural SciencesChemistryMedicinal ChemistryOrganic ChemistryPlant BiochemistryAlkaloid BiosynthesisHeterocyclic ChemistryMedicinal Plant KnowledgeMarine AlkaloidsPlant Alkaloids
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Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings
Christopher A. Lipinski, Franco Lombardo, Beryl W. Dominy et al. · Advanced Drug Delivery Reviews · 1997 · 11.2K citations
Pharmacy, Pharmacokinetics, Pharmacology +16
Molecular Properties That Influence the Oral Bioavailability of Drug Candidates
Daniel F. Veber, Stephen R. Johnson, Hung‐Yuan Cheng et al. · Journal of Medicinal Chemistry · 2002 · 8.1K citations
Pharmacy, Pharmacokinetics, Pharmacology +15
Fast Calculation of Molecular Polar Surface Area as a Sum of Fragment-Based Contributions and Its Application to the Prediction of Drug Transport Properties
Peter Ertl, Bernhard Rohde, Paul M. Selzer · Journal of Medicinal Chemistry · 2000 · 3K citations
Pharmacy, Chemistry, Pharmacology +15
Simple Selection Criteria for Drug-like Chemical Matter
Ingo Muegge, Sarah L. Heald, David R. Brittelli · Journal of Medicinal Chemistry · 2001 · 1.3K citations
Pharmacy, Medicinal Chemistry, Computational Medicinal Chemistry +11
Rapid calculation of polar molecular surface area and its application to the prediction of transport phenomena. 1. Prediction of intestinal absorption
David E. Clark · Journal of Pharmaceutical Sciences · 1999 · 618 citations
Pharmacy, Biophysics, Chemical Engineering +15