Journal of Investigative Medicine · 1999 · 436 citations · 51 references
These findings demonstrate an association between circadian phase, the relationship between the sleep-wake cycle and circadian phase, and morningness-eveningness in young adults. Furthermore, they demonstrate that age-related changes in phase angle cannot be attributed fully to an age-related shift toward morningness. These findings have important implications for understanding individual preferences in sleep-wake timing and age-related changes in the timing of sleep.
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Role of the CLOCK Protein in the Mammalian Circadian Mechanism
Nicholas Gekakis, David Staknis, Hubert B. Nguyen et al. · Science · 1998 · 2K citations
Mutagenesis and Mapping of a Mouse Gene, <i>Clock</i> , Essential for Circadian Behavior
Martha Hotz Vitaterna, David P. King, Anne-Marie Chang et al. · Science · 1994 · 1.6K citations