Activation of Raf-1/MEK-1/2/p42/44MAPK cascade alone is sufficient to uncouple LDL receptor expression from cell growth

All ras proteins are polyisoprenylated but only some are palmitoylated

John F. Hancock, Anthony I. Magee, Julie E. Childs et al. · Cell · 1989 · 1.8K citations

Protein Chemistry, Protein Function, Biochemistry +6

Inhibition of MAP Kinase Kinase Blocks the Differentiation of PC-12 Cells Induced by Nerve Growth Factor

Long Pang, Takeshi Sawada, Stuart J. Decker et al. · Journal of Biological Chemistry · 1995 · 904 citations · Full text

p21ras is modified by a farnesyl isoprenoid.

Patrick J. Casey, Patricia A. Solski, Channing J. Der et al. · Proceedings of the National Academy of Sciences · 1989 · 854 citations · Full text

Engineering, Yeast Peptides, Molecular Biology +16

Effects of p21 ^Cip1/Waf1 at Both the G ₁ /S and the G ₂ /M Cell Cycle Transitions: pRb Is a Critical Determinant in Blocking DNA Replication and in Preventing Endoreduplication

Alexander B. Niculescu, Xinbin Chen, Monique Smeets et al. · Molecular and Cellular Biology · 1998 · 723 citations · Full text

Raf-Induced Proliferation or Cell Cycle Arrest Is Determined by the Level of Raf Activity with Arrest Mediated by p21^Cip1

Douglas Woods, David Parry, Holly Cherwinski et al. · Molecular and Cellular Biology · 1997 · 646 citations · Full text

Cell Proliferation, Cell Cycle, Raf Activity +17