Evidence for improved DNA repair in the long-lived bowhead whale

Denis Firsanov, Max Zacher, Xiao Tian, Todd L. Sformo, Yang Zhao, Gregory Tombline, Jinlong Y. Lu, Zhizhong Zheng, Luigi Perelli, Enrico Gurreri,

Nature · 2025 · 31 citations · 68 references

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Abstract

, the bowhead whale maintains genome integrity through enhanced DNA repair. This strategy, which does not eliminate damaged cells but faithfully repairs them, may be contributing to the exceptional longevity and low cancer incidence in the bowhead whale.

References

68