Gut microbiota-mediated immunomodulation underlies the anti-tumor effects of a novel ginseng polysaccharide

Gut microbial metabolites facilitate anticancer therapy efficacy by modulating cytotoxic CD8+ T cell immunity

Yao He, Liuhui Fu, Yiping Li et al. · Cell Metabolism · 2021 · 667 citations · Full text

Life Sciences, Immunology, Oncology +16

Ginseng polysaccharides alter the gut microbiota and kynurenine/tryptophan ratio, potentiating the antitumour effect of antiprogrammed cell death 1/programmed cell death ligand 1 (anti-PD-1/PD-L1) immunotherapy

Jumin Huang, Di Liu, Yuwei Wang et al. · Gut · 2021 · 512 citations · Full text

Life Sciences, Immunology, Pharmacology +17

Activation of the JAK/STAT3 and PI3K/AKT pathways are crucial for IL-6 trans-signaling-mediated pro-inflammatory response in human vascular endothelial cells

Mulugeta M. Zegeye, Madelene Lindkvist, Knut Fälker et al. · Cell Communication and Signaling · 2018 · 351 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Gut microbiota-derived propionate reduces cancer cell proliferation in the liver

Laure B. Bindels, Paolo E. Porporato, Evelyne Dewulf et al. · British Journal of Cancer · 2012 · 307 citations · Full text

Life Sciences, Immunology, Oncology +16

The gut microbiota contributes to the development of <i>Staphylococcus aureus</i>-induced mastitis in mice

Xiaoyu Hu, Jian Guo, Caijun Zhao et al. · The ISME Journal · 2020 · 214 citations · Full text

Life Sciences, Immunology, Microbiology +12