Metabolic reprogramming of tumor-associated macrophages via adenosine-A2AR signaling drives cross-resistance in non-small cell lung cancer

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Epacadostat plus pembrolizumab versus placebo plus pembrolizumab in patients with unresectable or metastatic melanoma (ECHO-301/KEYNOTE-252): a phase 3, randomised, double-blind study

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CD73 promotes anthracycline resistance and poor prognosis in triple negative breast cancer

Sherene Loi, Sandra Pommey, Benjamin Haibe‐Kains et al. · Proceedings of the National Academy of Sciences · 2013 · 490 citations

Medicine, Immunology, Oncology +17

Adenosine mediates functional and metabolic suppression of peripheral and tumor-infiltrating CD8+ T cells

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Specific Decrease in B-Cell-Derived Extracellular Vesicles Enhances Post-Chemotherapeutic CD8+ T Cell Responses

Fanghui Zhang, Rongrong Li, Yunshan Yang et al. · Immunity · 2019 · 197 citations · Full text

Life Sciences, Immunology, Oncology +12