JAMA · 2025 · 12 citations · 4 references
Public HealthBiostatisticsCausal InferenceClinical EpidemiologyOutcomes ResearchClinical TrialsData AnalysisMissing Data HandlingMissing Data ImputationMissing Data MethodsStudy DesignHandling Missing Clinical DataMissing Data AdjustmentMissing Data Impact AssessmentMissing Data InferenceMissing Data Risk ManagementMissing-not-at-random ModelingMissingness MechanismsRandomized Clinical Trials
This JAMA Guide to Statistics and Methods explains tipping point analysis, which assesses how a range of hypothetical patterns in missing outcome data in a randomized clinical trial (RCT) would affect the study’s conclusions, and examines its use in an RCT of treatment for hypertension.
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Low-Dose Triple-Pill vs Standard-Care Protocols for Hypertension Treatment in Nigeria
Dike Ojji, Abdul Salam, Mahmoud U. Sani et al. · JAMA · 2024 · 35 citations · Full text