GLSP mitigates vascular aging by promoting Sirt7-mediated Keap1 deacetylation and Keap1-Nrf2 dissociation

Guobin Zheng, Heming Huang, Yun Zhao, Yuting Sun, Shangjing Liu, Feng He, Dan Li, Yuying Guo, Yaodong Miao, Mengxin Xu,

Theranostics · 2025 · 14 citations · 0 references

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Abstract

GLSP alleviates vascular aging by exerting antioxidant effects through the activation of the Sirt7-Nrf2 axis, providing a promising new strategy for delaying vascular aging, atherosclerosis and vascular calcification.