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FAK inhibition combined with the RAF-MEK clamp avutometinib overcomes resistance to targeted and immune therapies in BRAF V600E melanoma

Simone Lubrano, Rodolfo Daniel Cervantes‐Villagrana, Farhoud Faraji, Sydney I. Ramirez, Kuniaki Sato, Sendi Rafael Adame-Garcia, Nadia Arang, Damiano Cosimo Rigiracciolo, Paola Y. Anguiano Quiroz, Claudia Martini,

Cancer Cell · 2025 · 36 citations · 53 references

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53

Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles

Aravind Subramanian, Pablo Tamayo, Vamsi K. Mootha et al. · Proceedings of the National Academy of Sciences · 2005 · 56.7K citations · Full text

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Safety, Activity, and Immune Correlates of Anti–PD-1 Antibody in Cancer

Suzanne L. Topalian, F. Stephen Hodi, Julie R. Brahmer et al. · New England Journal of Medicine · 2012 · 12.7K citations · Full text

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Mutations of the BRAF gene in human cancer

Helen Davies, Graham R. Bignell, Charles Cox et al. · Nature · 2002 · 10.7K citations

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Cancer statistics, 2024

Rebecca L. Siegel, Angela N. Giaquinto, Ahmedin Jemal · CA A Cancer Journal for Clinicians · 2024 · 9K citations · Full text

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QuPath: Open source software for digital pathology image analysis

Peter Bankhead, Maurice B. Loughrey, José A. Fernández et al. · Scientific Reports · 2017 · 8.7K citations · Full text

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