Concepedia

Indoleamine 2, 3-dioxygenase 1 inhibition mediates the therapeutic effects in Parkinson's disease mice by modulating inflammation and neurogenesis in a gut microbiota dependent manner

Chen-Meng Qiao, Xiaoyu Ma, Lulu Tan, Yi-Meng Xia, Ting Li, Chun Cui, Wei-Jiang Zhao, Yan‐Qin Shen

Experimental Neurology · 2025 · 12 citations · 44 references

DOI

Concepts

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44

An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor

Christiane A. Opitz, Ulrike Litzenburger, Felix Sahm et al. · Nature · 2011 · 1.9K citations · Full text

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Adult hippocampal neurogenesis is abundant in neurologically healthy subjects and drops sharply in patients with Alzheimer’s disease

Elena P. Moreno‐Jiménez, Miguel Flor‐García, Julia Terreros‐Roncal et al. · Nature Medicine · 2019 · 1.6K citations

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Lipopolysaccharide-induced depressive-like behavior is mediated by indoleamine 2,3-dioxygenase activation in mice

Jason C. O’Connor, Mark A. Lawson, Caroline André et al. · Molecular Psychiatry · 2008 · 1.3K citations · Full text

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Protocol for the MPTP mouse model of Parkinson's disease

Vernice Jackson‐Lewis, Serge Przedborski · Nature Protocols · 2007 · 1.1K citations

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The Parkinson Pandemic—A Call to Action

E. Ray Dorsey, Bastiaan R. Bloem · JAMA Neurology · 2017 · 1.1K citations

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