Concepedia

Improved Pharmacokinetic Properties of a Polyethylene Glycol-Modified Form of Interferon-β-1a with Preserved in Vitro Bioactivity

R. Blake Pepinsky, Doreen LePage, Alan Gill, Abhijit Chakraborty, Sujata Vaidyanathan, Marie Green, Darren P. Baker, E. Whalley, Paula S. Hochman, Pauline L. Martin

Journal of Pharmacology and Experimental Therapeutics · 2001 · 77 citations · 21 references

DOI

Concepts

References

21

Intramuscular interferon beta‐1a for disease progression in relapsing multiple sclerosis

Diane L. Cookfair, Richard A. Rudick, Robert M. Herndon et al. · Annals of Neurology · 1996 · 2.4K citations

, , +12

Interferon beta‐1b is effective in relapsing‐remitting multiple sclerosis

Neurology · 1993 · 2.1K citations

, , +14

The interferon system. A bird's eye view of its biochemistry.

Ganes C. Sen, Péter Lengyel · Journal of Biological Chemistry · 1992 · 633 citations · Full text

, , +8

The uses and properties of PEG-linked proteins.

Cristina Delgado, G. E. Francis, Derek Fisher · PubMed · 1992 · 424 citations

, , +14

Structural and Functional Differences Between Glycosylated and Non-glycosylated Forms of Human Interferon-β (IFN-β)

Laura Runkel, Werner Meier, R. Blake Pepinsky et al. · Pharmaceutical Research · 1998 · 301 citations

, , +11