A Molecular Basis for the Different Local Anesthetic Affinities of Resting Versus Open and Inactivated States of the Sodium Channel

The Structure of the Potassium Channel: Molecular Basis of K ⁺ Conduction and Selectivity

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Prediction of protein antigenic determinants from amino acid sequences.

Thomas P. Hopp, Kenneth R. Woods · Proceedings of the National Academy of Sciences · 1981 · 3.7K citations · Full text

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Atomic Structure of Acetylcholinesterase from <i>Torpedo californica</i> : A Prototypic Acetylcholine-Binding Protein

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Local anesthetics: hydrophilic and hydrophobic pathways for the drug-receptor reaction.

Bertil Hille · The Journal of General Physiology · 1977 · 1.8K citations · Full text

Medicine, Pharmacology, Anesthesia +16

The Ionic Channels in Excitable Membranes

R. D. Keynes · Novartis Foundation symposium · 1975 · 1.7K citations

Natural Sciences, Biochemistry, Biophysics +14