Concepedia

M1 polarization of hepatic macrophages in cows with subclinical ketosis is an important cause of liver injury

Bi-Chen Zhao, Ming Li, Huijing Zhang, Jingyi Wang, Wanli Zhao, Yue Yang, Muhammad Usman, Juan J. Loor, Chuang Xu

Journal of Dairy Science · 2024 · 13 citations · 24 references

DOIFull text

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Concepts

Abstract

-positive cells. Overall, the present study revealed that the number of macrophages in liver is enhanced during subclinical ketosis and is dominated by pro-inflammatory macrophages (M1 macrophages). This could partly explain the increased risk of steatosis, fibrosis, and inflammatory response processes in these cows.

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