Comprehensive Integration of Single-Cell Data

Tim Stuart, Andrew Butler, Paul Hoffman, +7

Cell

EngineeringBiomedical Data IntegrationData ScienceSingle Cell SequencingMedicine +9

Integrated analysis of multimodal single-cell data

Yuhan Hao, Stephanie Hao, Erica Andersen‐Nissen, +22

Cell

UMAP: Uniform Manifold Approximation and Projection

Leland McInnes, John Healy, Nathaniel Saul, +1

The Journal of Open Source Software

Cellpose: a generalist algorithm for cellular segmentation

Carsen Stringer, Tim Wang, Michalis Michaelos, +1

Nature Methods

Image AnalysisGeneralist AlgorithmEngineeringBioimage AnalysisBiomedical Imaging +5

Identification and expression cloning of a leptin receptor, OB-R

Louis A. Tartaglia, Marlene Dembski, Xun Weng, +16

Cell

Signal TransductionMolecular PhysiologyHypothalamic PeptideLeptin ReceptorNeuropeptide Receptor +5

A Randomized, Controlled Trial of 3.0 mg of Liraglutide in Weight Management

F. Xavier Pi‐Sunyer, Arne Astrup, Ken Fujioka, +8

New England Journal of Medicine

Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus

Michael A. Cowley, James L. Smart, Marcelo Rubinstein, +5

Nature

NeuropeptidesAnorexigenic Pomc NeuronsArcuate NucleusBehavioral NeurosciencePhysiology +11

Rapid, reversible activation of AgRP neurons drives feeding behavior in mice

Michael J. Krashes, Shuichi Koda, Chian-Ping Ye, +6

Journal of Clinical Investigation

Food IntakeGastrointestinal Peptide HormoneNeural MechanismHypothalamic PeptideAppetite Control +16

NEUROPEPTIDE Y AND HUMAN PANCREATIC POLYPEPTIDE STIMULATE FEEDING BEHAVIOR IN RATS

John T. Clark, Pushpa S. Kalra, William R. Crowley, +1

Endocrinology

Leptin Action on GABAergic Neurons Prevents Obesity and Reduces Inhibitory Tone to POMC Neurons

Linh Vong, Chianping Ye, Zongfang Yang, +3

Neuron

ObesityMetabolic SyndromeNeuropeptidesLeptin ActionEnergy Homeostasis +13