Hepatocellular carcinoma epi-immunotherapy with polyion complex micelles co-delivering HDAC8 inhibitor and PD-L1 siRNA

NASH limits anti-tumour surveillance in immunotherapy-treated HCC

Dominik Pfister, Nicolás Gonzalo Núñez, Roser Pinyol et al. · Nature · 2021 · 1.2K citations · Full text

Life Sciences, Immunology, Oncology +17

β-Catenin Activation Promotes Immune Escape and Resistance to Anti–PD-1 Therapy in Hepatocellular Carcinoma

Marina Ruiz de Galarreta, Erin Bresnahan, Pedro Molina-Sánchez et al. · Cancer Discovery · 2019 · 894 citations · Full text

Medicine, Immunology, Oncology +17

A selective HDAC8 inhibitor potentiates antitumor immunity and efficacy of immune checkpoint blockade in hepatocellular carcinoma

Weiqin Yang, Yu Feng, Jingying Zhou et al. · Science Translational Medicine · 2021 · 162 citations

Medicine, Oncology, Pharmacology +16

Phase I/Ib Study of Pembrolizumab Plus Vorinostat in Advanced/Metastatic Non–Small Cell Lung Cancer

Jhanelle E. Gray, Andreas Saltos, Tawee Tanvetyanon et al. · Clinical Cancer Research · 2019 · 140 citations · Full text

Medicine, Oncology, Pharmacology +17

Protective effect of platinum nano-antioxidant and nitric oxide against hepatic ischemia-reperfusion injury

Jing Mu, Chunxiao Li, Yu Shi et al. · Nature Communications · 2022 · 137 citations · Full text

Life Sciences, Biotechnology, Materials Science +17