Concepedia

Gallic Acid Induces HeLa Cell Lines Apoptosis via the P53/Bax Signaling Pathway

Umut Sarı, Fuat Zaman, İlhan Özdemır, Şamil Öztürk, Mehmet Cudi Tuncer

Biomedicines · 2024 · 10 citations · 23 references

DOIFull text

Open access

Abstract

The obtained findings show that the gallic acid/doxorubicin combination applied to HeLa cells may be an alternative treatment against both the cytotoxic effect size and the side effects of the chemotherapy agent.

References

23

Direct Activation of Bax by p53 Mediates Mitochondrial Membrane Permeabilization and Apoptosis

Jerry E. Chipuk, Tomomi Kuwana, Lisa Bouchier‐Hayes et al. · Science · 2004 · 2K citations

, , +19

Quercetin, a Natural Flavonoid Interacts with DNA, Arrests Cell Cycle and Causes Tumor Regression by Activating Mitochondrial Pathway of Apoptosis

Shikha Srivastava, Ranganatha R. Somasagara, Mahesh Hegde et al. · Scientific Reports · 2016 · 475 citations · Full text

The Genomic and Transcriptomic Landscape of a HeLa Cell Line

Jonathan J. M. Landry, Paul Theodor Pyl, Tobias Rausch et al. · G3 Genes Genomes Genetics · 2013 · 473 citations · Full text

, , +17

Silibinin upregulates the expression of cyclin-dependent kinase inhibitors and causes cell cycle arrest and apoptosis in human colon carcinoma HT-29 cells

Chapla Agarwal, Rana P. Singh, Sivanandhan Dhanalakshmi et al. · Oncogene · 2003 · 223 citations

, , +7

Gallic acid inhibits the growth of HeLa cervical cancer cells via apoptosis and/or necrosis

Bo Ra You, Hwa Jin Moon, Yong Hwan Han et al. · Food and Chemical Toxicology · 2010 · 185 citations

, , +6