EMBO Reports · 2024 · 32 citations · 5 references
Life SciencesNeurologyNeuroscienceDementiaMonoclonal AntibodiesNeurodegenerationAlzheimer DiseaseAmyloid FormationDementia TreatmentNeurodegenerative Disease PharmacotherapyNeurodegenerative DiseasesNeurodegenerative DisordersAmyloid Beta AggregationAmyloid Beta PeptidesAmyloid Beta PlaquesAmyloid PlaquesTherapeutic Targeting Of Amyloid
The recent rejection of lecanemab by the European Medicines Agency despite its approval in other countries highlights the debate among researchers and regulatory bodies about the efficacy, safety, and underlying scientific basis of drugs to treat Alzheimer’s disease.
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Lecanemab in Early Alzheimer’s Disease
Christopher H. van Dyck, Chad J. Swanson, Paul Aisen et al. · New England Journal of Medicine · 2022 · 5.2K citations · Full text
Increases in amyloid-β42 slow cognitive and clinical decline in Alzheimer’s disease trials
Jesus Abanto, Alok Dwivedi, Bruno P. Imbimbo et al. · Brain · 2024 · 25 citations · Full text
Medicine, Neurology, Neuroscience +17