ASGR1 Deficiency Inhibits Atherosclerosis in Western Diet–Fed <i> ApoE ^−/− </i> Mice by Regulating Lipoprotein Metabolism and Promoting Cholesterol Efflux

Abstract

Inhibition of ASGR1 inhibits atherosclerosis in Western diet-fed <i>ApoE</i>^<i>-/-</i> mice, suggesting that inhibiting ASGR1 may serve as a novel therapeutic strategy to treat atherosclerosis and cardiovascular diseases.