Results in Engineering · 2024 · 34 citations · 43 references
EngineeringMaterials EngineeringMaterials ScienceAdditive ManufacturingBiomaterialsTissue EngineeringFracture ToughnessPowder Bed FusionScaffold DesignScaffold FabricationScaffolding SystemsTissue Engineering ScaffoldsAdditively Manufactured ScaffoldsBiomaterial ScaffoldsFatigue PerformanceFatigue Performance AnalysisLaser Powder Bed FusionScaffold ArchitectureScaffold Characterization
Additive manufacturing of Triply Periodic Minimum Surface scaffolds offers a promising solution for bone defect restoration and an alternative to traditional implants in hard tissue engineering. This study investigates the quasi-static and tension-compression cyclic properties of laser powder bed fusion-produced Ti6Al4V lattice-based architectures, specifically gyroid and diamond scaffold geometries. The scaffolds were designed to emulate the mechanical properties of bones, with pore sizes (650–1000 μm) suitable for tissue engineering, and porosities ranging from to 30–60 %. The quasi-static tensile properties of the stiffness and yield strength were characterized experimentally and validated numerically using the finite-element method. The results showed that the stiffness and tensile strength of the scaffolds were comparable to those of cortical bone, reducing the risk of scaffold failure. The influence of post-processing by heat treatment and hot isostatic pressing resulted in an increased fatigue limit and ductility compared with non-treated materials reported in the literature. Fractography analysis revealed that fatigue fracture initiation occurred at the outer surface of the skeleton structures, where the maximum tensile stress was concentrated. These findings support the assumption that the designed scaffolds accurately replicate the mechanical and fatigue characteristics of cortical bone, offering suitable alternatives for bone replacement and orthopedic implants. • Gyroid and diamond scaffolds were produced using a laser powder bed fusion process to emulate bone properties. • Scaffolds were tested under quasi-static tension and tension-compression high cycle fatigue loading. • The stiffness and tensile strength of the scaffolds were comparable to those of cortical bone. • Post-processing by heat treatment and HIP increased fatigue limit and ductility of scaffolds. • The designed scaffolds are suitable alternatives for bone replacement and orthopedic implants.
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Porous scaffolds for bone regeneration
Naghmeh Abbasi, Stephen Hamlet, Robert Love et al. · Journal of Science Advanced Materials and Devices · 2020 · 837 citations · Full text
F.S.L. Bobbert, Karel Lietaert, Ali Akbar Eftekhari et al. · Acta Biomaterialia · 2017 · 825 citations · Full text
Natural Sciences, Materials Engineering, Materials Science +15
Simon Van Bael, Yoke Chin Chai, Silvia Truscello et al. · Acta Biomaterialia · 2012 · 761 citations