Concepedia

Alpha-synuclein modulates the repair of genomic DNA double-strand breaks in a DNA-PKcs-regulated manner

Elizabeth P. Rose, Valerie R. Osterberg, Vera Gorbunova, Vivek K. Unni

Neurobiology of Disease · 2024 · 17 citations · 37 references

DOIFull text

Open access

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Abstract

as a potential therapeutic target.

References

37

Impaired Degradation of Mutant α-Synuclein by Chaperone-Mediated Autophagy

Ana María Cuervo, Leonidas Stefanis, Ross A. Fredenburg et al. · Science · 2004 · 2K citations

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Culturing hippocampal neurons

Gary Banker · Nature Protocols · 2006 · 1.7K citations

Synuclein: a neuron-specific protein localized to the nucleus and presynaptic nerve terminal

Luc Maroteaux, JT Campanelli, RH Scheller · Journal of Neuroscience · 1988 · 1.6K citations · Full text

, , +11

α-Synuclein aggregation nucleates through liquid–liquid phase separation

Soumik Ray, Nitu Singh, Rakesh Kumar et al. · Nature Chemistry · 2020 · 893 citations

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α-Synuclein impairs macroautophagy: implications for Parkinson’s disease

Ashley R. Winslow, Chien‐Wen Chen, Silvia Corrochano et al. · The Journal of Cell Biology · 2010 · 827 citations · Full text

, , +16