Salidroside alleviates ferroptosis in FAC-induced Age-related macular degeneration models by activating Nrf2/SLC7A11/GPX4 axis

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

Scott J. Dixon, Kathryn M. Lemberg, Michael R. Lamprecht et al. · Cell · 2012 · 18.1K citations · Full text

Life Sciences, Biochemistry, Cell Biology +10

Transcription Factor Nrf2 Coordinately Regulates a Group of Oxidative Stress-inducible Genes in Macrophages

Tetsuro Ishii, Ken Itoh, Satoru Takahashi et al. · Journal of Biological Chemistry · 2000 · 1.5K citations · Full text

Life Sciences, Biochemistry, Cell Biology +17

Glutathione depletion induces ferroptosis, autophagy, and premature cell senescence in retinal pigment epithelial cells

Yun Sun, Yingfeng Zheng, Chunxiao Wang et al. · Cell Death and Disease · 2018 · 542 citations · Full text

Life Sciences, Cell Biology, Ophthalmology +17

Melatonin Suppresses Ferroptosis Induced by High Glucose via Activation of the Nrf2/HO-1 Signaling Pathway in Type 2 Diabetic Osteoporosis

Hongdong Ma, Xindong Wang, Weilin Zhang et al. · Oxidative Medicine and Cellular Longevity · 2020 · 389 citations · Full text

Medicine, Cell Biology, Endocrinology +17

Nrf1 and Nrf2 Regulate Rat Glutamate-Cysteine Ligase Catalytic Subunit Transcription Indirectly via NF-κB and AP-1

Heping Yang, Nathaniel Magilnick, Candy Lee et al. · Molecular and Cellular Biology · 2005 · 255 citations

Life Sciences, Biochemistry, Molecular Biology +16