Paeoniflorin inhibits PRAS40 interaction with Raptor to activate mTORC1 to reverse excessive autophagy in airway epithelial cells for asthma

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Plasma interleukin-6 concentrations, metabolic dysfunction, and asthma severity: a cross-sectional analysis of two cohorts

Michael C. Peters, Gregory A. Hawkins, Annette T. Hastie et al. · The Lancet Respiratory Medicine · 2016 · 535 citations · Full text

Life Sciences, Immunology, Clinical Immunology +12

The burden of asthma, hay fever and eczema in children in 25 countries: GAN Phase I study

Luis García‐Marcos, M. Innes Asher, Neil Pearce et al. · European Respiratory Journal · 2022 · 214 citations · Full text

Public Health, Child Health, Pediatrics +11

Regulation of Proline-rich Akt Substrate of 40 kDa (PRAS40) Function by Mammalian Target of Rapamycin Complex 1 (mTORC1)-mediated Phosphorylation

Lifu Wang, Thurl E. Harris, John C. Lawrence · Journal of Biological Chemistry · 2008 · 184 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13

Autophagy Activation in Asthma Airways Remodeling

Kielan Darcy McAlinden, Deepak A. Deshpande, Saeid Ghavami et al. · American Journal of Respiratory Cell and Molecular Biology · 2018 · 165 citations · Full text

Life Sciences, Cell Biology, Pharmacology +17