Concepedia

Ligustilide alleviates oxidative stress during renal ischemia-reperfusion injury through maintaining Sirt3-dependent mitochondrial homeostasis

Xia Kang, Zeya Jin, Qiangmin Qiu, Yujie Zhou, Yifan Lu, Tao Qiu, Jiangqiao Zhou, Zhongbao Chen

Phytomedicine · 2024 · 18 citations · 25 references

DOIFull text

Open access

Abstract

Our findings demonstrated that LIG alleviated oxidative stress during renal I/R injury through maintaining Sirt3-dependent mitochondrial homeostasis. Overall, our data raised the possibility of LIG as a novel therapy for renal I/R injury.

References

25

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Inhibition of Brd4 alleviates renal ischemia/reperfusion injury-induced apoptosis and endoplasmic reticulum stress by blocking FoxO4-mediated oxidative stress

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Neutrophil peptidyl arginine deiminase-4 has a pivotal role in ischemia/reperfusion-induced acute kidney injury

Wesley M. Raup‐Konsavage, Yanming Wang, Wei Wei Wang et al. · Kidney International · 2017 · 187 citations · Full text

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Ligustilide ameliorates hippocampal neuronal injury after cerebral ischemia reperfusion through activating PINK1/Parkin-dependent mitophagy

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Zhiqing Diao, Qianzhao Ji, Zeming Wu et al. · Nucleic Acids Research · 2021 · 158 citations · Full text

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