Concepedia

Development of poly (lactic-co-glycolic acid) (PLGA) based implants using hot melt extrusion (HME) for sustained release of drugs: The impacts of PLGA’s material characteristics

Fengyuan Yang, Ryan Stahnke, Kamaru Lawal, Cory J. Mahnen, Patrick Duffy, Shuyu Xu, Thomas Dürig

International Journal of Pharmaceutics · 2024 · 15 citations · 37 references

Concepts

Natural SciencesBioengineeringBiomedical EngineeringBiocompatibilityBiomaterialsDrug DeliveryDrug Delivery BiomaterialsImplant MaterialsImplantable BiomaterialsImplantable Biomedical DevicesImplantable Drug Delivery SystemsExtrusionImplant FabricationImplantable Drug Delivery DevicesManufacturing Of ImplantsPoly(lactic-co-glycolic Acid)Polymeric ImplantsSustained Release BiomaterialsSustained Release Kinetics

References

37

Poly Lactic-co-Glycolic Acid (PLGA) as Biodegradable Controlled Drug Delivery Carrier

Hirenkumar K. Makadia, Steven J. Siegel · Polymers · 2011 · 4.6K citations · Full text

Engineering, Bioengineering, Biomedical Engineering +17

How Autocatalysis Accelerates Drug Release from PLGA-Based Microparticles: A Quantitative Treatment

Juergen Siepmann, K. Elkharraz, F. Siepmann et al. · Biomacromolecules · 2005 · 299 citations

Pharmacy, Molecular Pharmaceutics, Pharmaceutics +17

Evaluation of in vivo–in vitro release of dexamethasone from PLGA microspheres

Banu S. Zolnik, Diane J. Burgess · Journal of Controlled Release · 2008 · 283 citations

Pharmacy, Bioengineering, Pharmaceutics +14

PLGA-based drug delivery systems: Importance of the type of drug and device geometry

Diana Klose, F. Siepmann, K. Elkharraz et al. · International Journal of Pharmaceutics · 2007 · 262 citations

Pharmacy, Bioengineering, Pharmaceutics +14

Flexible, sticky, and biodegradable wireless device for drug delivery to brain tumors

Jongha Lee, Hye Rim Cho, Gi Doo et al. · Nature Communications · 2019 · 243 citations · Full text

Engineering, Bioengineering, Biomedical Engineering +14