Concepedia

Biomimetic nanoparticles with enhanced rapamycin delivery for autism spectrum disorder treatment via autophagy activation and oxidative stress modulation

Chenlin Miao, Yizhe Shen, Yue Lang, Hui Li, Yan Gong, Yamei Liu, Huafei Li, Byron C. Jones, Fuxue Chen, Shini Feng

Theranostics · 2024 · 19 citations · 25 references

DOIFull text

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Concepts

Abstract

The therapeutic potential of SCM@RAPA in managing ASD signifies a paradigm shift in autism drug treatment, holding promise for clinical interventions in diverse neurological conditions.

References

25

Integrating single-cell transcriptomic data across different conditions, technologies, and species

Andrew Butler, Paul Hoffman, Peter Smibert et al. · Nature Biotechnology · 2018 · 14.7K citations · Full text

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Loss of mTOR-Dependent Macroautophagy Causes Autistic-like Synaptic Pruning Deficits

Guomei Tang, Kathryn Gudsnuk, Sheng‐Han Kuo et al. · Neuron · 2014 · 1.2K citations · Full text

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mTOR kinase structure, mechanism and regulation

Haijuan Yang, Derek G. Rudge, Joseph D. Koos et al. · Nature · 2013 · 1.1K citations

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Autistic-like behaviour and cerebellar dysfunction in Purkinje cell Tsc1 mutant mice

Peter T. Tsai, Court Hull, YunXiang Chu et al. · Nature · 2012 · 911 citations · Full text

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Erythrocyte-cancer hybrid membrane-camouflaged melanin nanoparticles for enhancing photothermal therapy efficacy in tumors

Qin Jiang, Yao Liu, Ranran Guo et al. · Biomaterials · 2018 · 397 citations

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