Leveraging real-world data to predict cancer cachexia stage, quality of life, and survival in a racially and ethnically diverse multi-institutional cohort of treatment-naïve patients with pancreatic ductal adenocarcinoma

Jennifer B. Permuth, Margaret A. Park, Dung‐Tsa Chen, Toni L. Basinski, Benjamin D. Powers, Clement K. Gwede, Kaleena B. Dezsi, Maria F. Gomez, Shraddha Vyas, Tiago Biachi,

Frontiers in Oncology · 2024 · 12 citations · 92 references

DOIFull text

Open access

Abstract

Using clinical, nutritional, and functional criteria, nearly one-quarter of the PDAC cases in our diverse, multi-institutional cohort had PCa and 62.5% had Ca or RCa at the time of diagnosis. The PCa estimate is higher than that reported in prior studies. We recommend these criteria be used to aid in CC classification, monitoring, and management of all incident PDAC cases. Findings also highlight the recommendation for continued emotional support, assistance in alleviating pain, and supportive care needs throughout the PDAC treatment journey.

References

92