Baicalein upregulates macrophage TREM2 expression via TrKB-CREB1 pathway to attenuate acute inflammatory injury in acute-on-chronic liver failure

Acute-on-Chronic Liver Failure Is a Distinct Syndrome That Develops in Patients With Acute Decompensation of Cirrhosis

Richard Moreau, Rajiv Jalan, Pere Ginès et al. · Gastroenterology · 2013 · 3K citations

Medicine, Internal Medicine, Critical Care Medicine +11

Blood metabolomics uncovers inflammation-associated mitochondrial dysfunction as a potential mechanism underlying ACLF

Richard Moreau, Joan Clària, Ferrán Aguilar et al. · Journal of Hepatology · 2019 · 352 citations · Full text

Life Sciences, Biochemistry, Cell Biology +12

CREB Family Transcription Factors Are Major Mediators of BDNF Transcriptional Autoregulation in Cortical Neurons

Eli‐Eelika Esvald, Jürgen Tuvikene, Alex Sirp et al. · Journal of Neuroscience · 2020 · 251 citations · Full text

Life Sciences, Molecular Biology, Neuroscience +14

Baicalein ameliorates ulcerative colitis by improving intestinal epithelial barrier via AhR/IL-22 pathway in ILC3s

Yanyang Li, Xiaojing Wang, Yu‐Lin Su et al. · Acta Pharmacologica Sinica · 2021 · 247 citations · Full text

Life Sciences, Immunology, Pharmacology +16

Prolonged hypernutrition impairs TREM2-dependent efferocytosis to license chronic liver inflammation and NASH development

Xiaochen Wang, Qifeng He, Chuanli Zhou et al. · Immunity · 2022 · 233 citations · Full text

Life Sciences, Immunology, Nutritional Sciences +16