Exogenous iron caused osteocyte apoptosis, increased RANKL production, and stimulated bone resorption through oxidative stress in a murine model

Evidence for osteocyte regulation of bone homeostasis through RANKL expression

Tomoki Nakashima, Mikihito Hayashi, Takanobu Fukunaga et al. · Nature Medicine · 2011 · 1.7K citations

Medicine, Cell Biology, Physiology +16

Matrix-embedded cells control osteoclast formation

Jinhu Xiong, Melda Onal, Robert L. Jilka et al. · Nature Medicine · 2011 · 1.3K citations · Full text

Medicine, Cell Biology, Bone Metabolism +11

Structure of hepcidin-bound ferroportin reveals iron homeostatic mechanisms

Christian B. Billesbølle, Caleigh M. Azumaya, Rachael C. Kretsch et al. · Nature · 2020 · 338 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13

Bone loss caused by iron overload in a murine model: importance of oxidative stress

Jaime Tsay, Zheiwei Yang, F. Patrick Ross et al. · Blood · 2010 · 335 citations · Full text

Medicine, Biochemistry, Physiology +17

Identification of apoptotic changes in osteocytes in normal and pathological human bone

B Noble, Hazel Y. Stevens, N. Loveridge et al. · Bone · 1997 · 231 citations

Medicine, Cell Biology, Pathology +14