Concepedia

Combination of menin and kinase inhibitors as an effective treatment for leukemia with NUP98 translocations

Hongzhi Miao, Dong Chen, James Ropa, Trupta Purohit, EunGi Kim, Maria‐Luisa Sulis, Adolfo A. Ferrando, Tomasz Cierpicki, Jolanta Grembecka

Leukemia · 2024 · 21 citations · 33 references

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33

Drug Combination Studies and Their Synergy Quantification Using the Chou-Talalay Method

Ting‐Chao Chou · Cancer Research · 2010 · 5.7K citations

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An embryonic stem cell–like gene expression signature in poorly differentiated aggressive human tumors

Ittai Ben‐Porath, Matthew Thomson, Vincent J. Carey et al. · Nature Genetics · 2008 · 2.6K citations · Full text

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The reactome pathway knowledgebase 2022

Marc Gillespie, Bijay Jassal, Ralf Stephan et al. · Nucleic Acids Research · 2021 · 2.5K citations · Full text

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The Menin Tumor Suppressor Protein Is an Essential Oncogenic Cofactor for MLL-Associated Leukemogenesis

Akihiko Yokoyama, Tim C. P. Somervaille, Kevin S. Smith et al. · Cell · 2005 · 670 citations · Full text

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Menin Critically Links MLL Proteins with LEDGF on Cancer-Associated Target Genes

Akihiko Yokoyama, Michael L. Cleary · Cancer Cell · 2008 · 542 citations · Full text

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