Concepedia

Publication | Open Access

Guizhitongluo Tablet inhibits atherosclerosis and foam cell formation through regulating Piezo1/NLRP3 mediated macrophage pyroptosis

DOIFull Paper Access

22

Citations

30

References

2024

Year

Xianmei Pan, Honglin Xu, Zhiqiang Ding, Shangfei Luo, Zhifang Li, Rentao Wan, Jintao Jiang, Xiaoting Chen, Silin Liu, Zixin Chen,
Phytomedicine

Abstract

The present study suggests that GZTLT inhibits vascular inflammation and macrophage pyroptosis through the Piezo1/NLRP3 signaling pathway, thereby delaying AS development. Our finding provides a potential target for AS treatment and drug discovery.

References

YearCitations

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