Epigenetic scars in regulatory T cells are retained after successful treatment of chronic hepatitis C with direct-acting antivirals

GREAT improves functional interpretation of cis-regulatory regions

Cory Y. McLean, Dave Bristor, Michael Hiller et al. · Nature Biotechnology · 2010 · 5K citations

Life Sciences, Bioinformatics, Molecular Biology +12

JASPAR 2022: the 9th release of the open-access database of transcription factor binding profiles

Jaime A. Castro-Mondragón, Rafael Riudavets Puig, Ieva Rauluševičiūtė et al. · Nucleic Acids Research · 2021 · 2.1K citations · Full text

Life Sciences, Bioinformatics, Molecular Biology +14

The transcription factor T-bet controls regulatory T cell homeostasis and function during type 1 inflammation

Meghan A. Koch, Glady’s Tucker-Heard, Nikole Perdue et al. · Nature Immunology · 2009 · 1.2K citations · Full text

Life Sciences, Immunology, Molecular Biology +16

Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control TH2 responses

Ye Zheng, Ashutosh Chaudhry, Arnold Kas et al. · Nature · 2009 · 931 citations

Life Sciences, Immunology, Molecular Biology +12

Single-Cell Analysis of Crohn’s Disease Lesions Identifies a Pathogenic Cellular Module Associated with Resistance to Anti-TNF Therapy

J.P. Martin, Christie Chang, Gilles Boschetti et al. · Cell · 2019 · 898 citations · Full text

Life Sciences, Cell Biology, Immunology +17