Nature Sustainability · 2024 · 42 citations · 10 references
PharmacyMedicinal ChemistryPharmacologyDrug DesignDrug DiscoveryGreen ChemistryDesign Of Safer ChemicalsDrug FormulationDrug-likeness AssessmentLead Compound DesignPhysicochemical Property OptimizationPotency OptimizationDrug Product DevelopmentMedicinal Chemistry ApplicationsProperty-based Drug DesignSafer Pharmaceutical DesignSmall Molecule Drug Design
The pervasive contamination of ecosystems with active pharmaceutical ingredients poses a serious threat to biodiversity, ecosystem services and public health. Urgent action is needed to design greener drugs that maintain efficacy but also minimize environmental impact.
10
Pharmaceutical pollution of the world’s rivers
John L. Wilkinson, Alistair B.A. Boxall, Dana W. Kolpin et al. · Proceedings of the National Academy of Sciences · 2022 · 1.5K citations · Full text
Marc Bourgin, Birgit Beck, M. Boehler et al. · Water Research · 2017 · 521 citations · Full text
Engineering, Chemical Engineering, Environmental Engineering +17