Concepedia

Some pyrimidohexahydroquinoline candidates: synthesis, DFT, cytotoxic activity evaluation, molecular docking, and <i>in silico</i> studies

Sayed K. Ramadan, Hisham S. M. Abd‐Rabboh, Amal A. Abdel Hafez, Wael S. I. Abou‐Elmagd

RSC Advances · 2024 · 27 citations · 40 references

DOIFull text

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Concepts

Abstract

Hexahydroquinolines were prepared and supported by in silico studies. Thiosemicarbazide and thiazolidinone derivatives showed the highest in vitro antiproliferative potency against liver, breast, prostate, and colon cancer cell lines.

References

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