Exploring the intricacies of calcium dysregulation in ischemic stroke: Insights into neuronal cell death and therapeutic strategies

p53 Opens the Mitochondrial Permeability Transition Pore to Trigger Necrosis

Angelina V. Vaseva, Natalie D. Marchenko, Kyungmin Ji et al. · Cell · 2012 · 734 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +14

Contacts between the endoplasmic reticulum and other membranes in neurons

Yumei Wu, Christina Whiteus, C. Shan Xu et al. · Proceedings of the National Academy of Sciences · 2017 · 512 citations · Full text

Life Sciences, Neurobiology, Neuroscience +14

Projected Global Trends in Ischemic Stroke Incidence, Deaths and Disability-Adjusted Life Years From 2020 to 2030

Liyuan Pu, Li Wang, Ruijie Zhang et al. · Stroke · 2023 · 467 citations · Full text

Public Health, Demography, Population Health Sciences +16

UPR proteins IRE1 and PERK switch BiP from chaperone to ER stress sensor

Megan C Kopp, Natacha Larburu, Vinoth Durairaj et al. · Nature Structural & Molecular Biology · 2019 · 407 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +10

Pre‐ischemia melatonin treatment alleviated acute neuronal injury after ischemic stroke by inhibiting endoplasmic reticulum stress‐dependent autophagy via <scp>PERK</scp> and <scp>IRE</scp>1 signalings

Dayun Feng, Bao Wang, Lei Wang et al. · Journal of Pineal Research · 2017 · 276 citations

Life Sciences, Neuroscience, Pharmacology +17